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CSTF2T 抗体 (AA 566-616)

CSTF2T 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7448495
发货至: 中国
  • 抗原 See all CSTF2T 抗体
    CSTF2T (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T))
    抗原表位
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 566-616
    适用
    • 26
    • 9
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    宿主
    • 23
    • 3
    克隆类型
    • 25
    • 1
    多克隆
    标记
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CSTF2T antibody is un-conjugated
    应用范围
    • 17
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    原理
    Rabbit anti-CSTF2T/TauCSTF64 IHC Antibody, Affinity Purified
    预测反应
    Mouse,Rat,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Gorilla,Chimpanzee,African elephant,West Indian ocean coelacanth,White-tufted-ear marmoset,Soybean,Chinese hamster,Small-eared galago,Naked mole rat,Thirteen-lined ground squirrel,Northern white-cheeked gibbon
    纯化方法
    Affinity Purified
    免疫原
    Between AA 566 and 616
    亚型
    IgG
    Top Product
    Discover our top product CSTF2T Primary Antibody
  • 应用备注
    1:100 - 1:500
    限制
    仅限研究用
  • 浓度
    250 μg/mL
    缓冲液
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    CSTF2T (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T))
    别名
    CSTF2T/TauCSTF64 (CSTF2T 产品)
    别名
    64kDa antibody, C77975 antibody, tCstF-64 antibody, tauCstF-64 antibody, CstF-64T antibody, cleavage stimulation factor, 3' pre-RNA subunit 2, tau antibody, cleavage stimulation factor subunit 2 tau variant antibody, cleavage stimulation factor subunit 2, tau variant antibody, Cstf2t antibody, CSTF2T antibody
    背景
    Background: CSTF2T, also known as tauCSTF-64, is a paralog of CstF-64, a component of the cleavage stimulation factor (CstF) that processes 3'-end formation and polyadenylation of mRNAs. The human CSTF2T/TauCSTF64 gene is located at 10q22-23, a site associated with neurological problems and male infertility. CSTF2T is expressed in all tissues and throughout meiosis in male germ cells. CstF-64 is also expressed ubiquitously, however because it is located on the X chromosome, its expression is temporarily silenced in germ cells by meiotic sex chromosome inactivation. During this inactivation, it is hypothesized that CSTF2T/TauCSTF64 can compensate for the loss of CstfF-64 expression. Recently, targeted disruption of CSTF2T/TauCSTF64 in mice has been shown to cause aberrant spermatogenesis and infertility providing more evidence for its importance in spermatogenesis.
    基因ID
    23283
    NCBI登录号
    NP_056050
    UniProt
    Q9H0L4
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