eIF4EBP1 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for eIF4EBP1 抗体 (C-Term) (ABIN7448395)
抗原
See all eIF4EBP1 (EIF4EBP1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- Rabbit anti-4EBP1 IHC Antibody, Affinity Purified
-
预测反应
- Rat,Rabbit,Pig,Orangutan,Monkey,Gorilla,Chimpanzee,Chinese hamster,Thirteen-lined ground squirrel,Crab-eating macaque
-
纯化方法
- Affinity Purified
-
免疫原
- Between AA 75 and C-term
-
亚型
- IgG
-
-
-
-
应用备注
- 1:100 - 1:500
-
限制
- 仅限研究用
-
-
-
浓度
- 50 μg/mL
-
缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
-
别名
- 4EBP1
-
背景
- Background: Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) binds directly to eIF4E to inhibit complex assembly for translation initiation. 4EBP1 is part of a family of translation repressor proteins. 4EBP1 is directly phosphorylated by the mTORC1 complex during growth factor stimulation of cells. Phosphorylation of 4EBP1 causes its release from eIF4E to allow translation to proceed.
-
基因ID
- 1978
-
NCBI登录号
- NP_004086
-
UniProt
- Q13541
-
途径
- MAPK Pathway, PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Regulation of Cell Size, BCR Signaling
抗原
-