SMG7 抗体 (Internal Region)
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- 抗原 See all SMG7 抗体
- SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMG7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Affinity purification
- 免疫原
- Synthesized peptide derived from the Internal region of human SMG7
- 亚型
- IgG
- Top Product
- Discover our top product SMG7 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))
- 别名
- SMG7 (SMG7 产品)
- 别名
- 9430023P16Rik antibody, mKIAA0250 antibody, C1orf16 antibody, EST1C antibody, SGA56M antibody, Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) antibody, SMG7, nonsense mediated mRNA decay factor antibody, Smg7 antibody, SMG7 antibody
- 背景
- Breast cancer-associated antigen SGA-56M,C1orf16,EST1 like protein C,EST1 telomerase component homolog C,EST1-like protein C,EST1C,ever shorter telomeres 1C,FLJ23717,hSMG-7,nonsense mediated mRNA decay factor (C. elegans),Protein SMG7,SGA56M,SMG 7,SMG-7 homolog,Smg7,SMG7,This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD), a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.SMG7 (SMG7, Nonsense Mediated MRNA Decay Factor) is a Protein Coding gene. Among its related pathways are Gene Expression and Viral mRNA Translation. GO annotations related to this gene include protein phosphatase 2A binding. An important paralog of this gene is SMG6.
- 分子量
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Observed_MW: 127kDa
Calculated_MW: 127kDa
- 基因ID
- 9887
- UniProt
- Q92540
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