ZNF451 抗体
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- 抗原 See all ZNF451 抗体
- ZNF451 (Zinc Finger Protein 451 (ZNF451))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZNF451 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human ZNF451 (NP_001026794.1).
- 亚型
- IgG
- Top Product
- Discover our top product ZNF451 Primary Antibody
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anti-Zinc Finger Protein 451 (ZNF451) (C-Term) antibody
ZNF451 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, 兔, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 451 (ZNF451) (AA 600-900) antibodyZNF451 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:200-1:2000
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- ZNF451 (Zinc Finger Protein 451 (ZNF451))
- 别名
- ZNF451 (ZNF451 产品)
- 别名
- COASTER antibody, dJ417I1.1 antibody, 4930515K21Rik antibody, 4933435G09Rik antibody, AI596398 antibody, Kiaa0576-hp antibody, Znf451 antibody, mKIAA1702 antibody, zinc finger protein 451 antibody, ZNF451 antibody, Zfp451 antibody
- 背景
- ZNF451,COASTER,dJ417I1.1,E3 SUMO-protein ligase, has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494). Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation (By similarity). Has no activity with SUMO1 (PubMed:26524493). Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11' (PubMed:26524493). Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9'. Plays a role in regulating the transcription of AR targets.
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 63 kDa/115 kDa/121 kDa
- 基因ID
- 26036
- UniProt
- Q9Y4E5
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