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Bcl-2 抗体 (AA 41-54) (PE)

This anti-Bcl-2 antibody is a 小鼠 单克隆 antibody detecting Bcl-2 in FACS. Suitable for 人.
产品编号 ABIN7272018
发货至: 中国

Quick Overview for Bcl-2 抗体 (AA 41-54) (PE) (ABIN7272018)

抗原

See all Bcl-2 (BCL2) 抗体
Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Bcl-2 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

质量等级

GMP Grade

克隆位点

1E2
  • 抗原表位

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    AA 41-54

    原理

    BCL-2 PE Antibody

    产品特性

    The clone 100, a mouse monoclonal antibody, recognizes a 239 amino acid ~25 kDa human apoptosis regulator oncoprotein known as Bcl-2. It is an intracellular, integral membrane protein containing up to 4 Bcl-2 homology (BH) motifs which are found primarily in the nuclear envelope, endoplasmic reticulum and outer mitochondrial membrane. Bcl-2 is a conserved anti-apoptotic protein and plays important roles in the management of normal immunity. Nonrandom translocations with breakpoint at band q21 on chromosome 18 may cause bcl-2 gene deregulation and contribute to neoplastic transformation in human lymphomas.

    纯化方法

    Purified

    纯度

    >95 %

    免疫原

    Human BCL-2 synthetic peptide aa. 41-54

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2-8°C, Conjugated antibodies should never be frozen.
  • 抗原

    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

    别名

    BCL-2

    基因ID

    596

    UniProt

    P10415

    途径

    MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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