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TTLL12 抗体

KO Validated TTLL12 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7271032
发货至: 中国
  • 抗原 See all TTLL12 products
    TTLL12 (Tubulin tyrosine Ligase-Like Family, Member 12 (TTLL12))
    适用
    • 8
    • 4
    • 4
    • 2
    • 1
    宿主
    • 4
    • 4
    克隆类型
    • 4
    • 4
    多克隆
    标记
    • 8
    This TTLL12 antibody is un-conjugated
    应用范围
    • 8
    • 5
    • 4
    • 3
    • 3
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    [KO Validated] TTLL12 Rabbit pAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    质量等级
    KO Validated
    免疫原
    Recombinant protein of human TTLL12.
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TTLL12 (Tubulin tyrosine Ligase-Like Family, Member 12 (TTLL12))
    别名
    TTLL12 (TTLL12 产品)
    别名
    zgc:55343 antibody, dJ526I14.2 antibody, RGD1305319 antibody, BC055368 antibody, D430005B17 antibody, tubulin tyrosine ligase-like family, member 12 antibody, tubulin tyrosine ligase like 12 antibody, Tubulin--tyrosine ligase-like protein 12 antibody, ttll12 antibody, TTLL12 antibody, ttll-12 antibody, Ttll12 antibody
    背景
    Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues. Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3. Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability. During RNA virus-mediated infection, acts as a negative regulator of the DDX58/RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE.,TTLL12,dJ526I14.2,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,TTLL12
    分子量
    74kDa
    基因ID
    23170
    UniProt
    Q14166
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