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- 抗原 See all TTC3 抗体
- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
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抗原表位
- AA 1400-1700
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TTC3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- TTC3 Rabbit pAb
- 序列
- IASETQILEG SLGISVKSHC STGDAHTVLS ESNRNDEHCG NSNNKCEVIP ESTSAVTNIP HVQMVAIQVS WNIIHQEVNT EPYNPFEERQ GEISRIEKEH QVLQDQLQEV YENYEQIKLK GLEETRDLEE KLKRHLEENK ISKTELDWFL QDLEREIKKW QQEKKEIQER LKSLKKKIKK VSNASEMYTQ KNDGKEKEHE LHLDQSLEIS NTLTNEKMKI EEYIKKGKED YEESHQRAVA AEVSVLENWK ESEVYKLQIM ESQAEAFLKK LGLISRDPAA YPDMESDIRS WELFLSNVTK E
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1400-1700 of human TTC3 (NP_003307.3).
- 亚型
- IgG
- Top Product
- Discover our top product TTC3 Primary Antibody
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anti-Tetratricopeptide Repeat Domain 3 (TTC3) (AA 1-110) antibody
TTC3 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tetratricopeptide Repeat Domain 3 (TTC3) (AA 1-110) antibodyTTC3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2D10 unconjugated
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- 应用备注
- WB,1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
- 别名
- TTC3 (TTC3 产品)
- 别名
- DCRR1 antibody, RNF105 antibody, TPRDIII antibody, 2610202A04Rik antibody, AA409221 antibody, D16Ium21 antibody, D16Ium21e antibody, TPRD antibody, mKIAA4119 antibody, TTC3 antibody, tetratricopeptide repeat domain 3 antibody, E3 ubiquitin-protein ligase TTC3 antibody, TTC3 antibody, Ttc3 antibody, LOC100562480 antibody
- 背景
- E3 ubiquitin-protein ligase which catalyzes the formation of 'Lys-48'-polyubiquitin chains. Mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3 in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Positively regulates TGFB1-induced epithelial-mesenchymal transition and myofibroblast differentiation by mediating the ubiquitination and subsequent degradation of SMURF2. Regulates neuronal differentiation by regulating actin remodeling and Golgi organization via a signaling cascade involving RHOA, CIT and ROCK. Inhibits cell proliferation.,TTC3,DCRR1,RNF105,TPRDIII,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,TTC3
- 分子量
- 194kDa/203kDa/229kDa
- 基因ID
- 7267
- UniProt
- P53804
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