2900016I08Rik antibody, A730055F12Rik antibody, AU042072 antibody, Srebf1 antibody, target of myb1 like 2 membrane trafficking protein antibody, target of myb1 like 2 membrane trafficking protein L homeolog antibody, target of myb1-like 2 (chicken) antibody, TOM1L2 antibody, tom1l2.L antibody, Tom1l2 antibody
背景
This gene belongs to a small gene family whose members have an N-terminal VHS domain followed by a GAT domain, domains which typically participate in vesicular trafficking. The canonical protein encoded by this gene also has a C-terminal clathrin binding motif. This protein has been shown to interact with Tollip, clathrin and ubiquitin and is thought to play a role in endosomal sorting. This gene resides in the 3.7 Mb deletion of chromosome region 17p11.2 that is associated with Smith-Magenis syndrome. Alternative splicing results in multiple transcript variants encoding distinct proteins.,TOM1L2