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TNKS 抗体 (AA 1050-1150)

TNKS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7270725
发货至: 中国
  • 抗原 See all TNKS 抗体
    TNKS (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))
    抗原表位
    • 10
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1050-1150
    适用
    • 37
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 32
    • 3
    • 1
    • 1
    克隆类型
    • 34
    • 3
    多克隆
    标记
    • 25
    • 4
    • 2
    • 2
    • 2
    • 2
    This TNKS antibody is un-conjugated
    应用范围
    • 31
    • 21
    • 18
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    原理
    TNKS Rabbit pAb
    序列
    EQITLDVLAD MGHEELKEIG INAYGHRHKL IKGVERLLGG QQGTNPYLTF HCVNQGTILL DLAPEDKEYQ SVEEEMQSTI REHRDGGNAG GIFNRYNVIR I
    交叉反应
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 1050-1150 of human TNKS (NP_003738.2).
    亚型
    IgG
    Top Product
    Discover our top product TNKS Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TNKS (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))
    别名
    TNKS (TNKS 产品)
    别名
    wu:fe02c12 antibody, ARTD5 antibody, PARP-5a antibody, PARP5A antibody, PARPL antibody, TIN1 antibody, TINF1 antibody, TNKS1 antibody, pART5 antibody, 4930554K12Rik antibody, AI662855 antibody, C86528 antibody, D130072O21Rik antibody, TANK1 antibody, mTNKS1 antibody, tankyrase-1 antibody, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b antibody, tankyrase antibody, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase antibody, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 S homeolog antibody, tnksb antibody, TNKS antibody, Tnks antibody, tnks2.S antibody
    背景
    Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates PARsylation of TERF1, thereby contributing to the regulation of telomere length. Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. May be involved in spindle pole assembly through PARsylation of NUMA1. Stimulates 26S proteasome activity.,TNKS,ARTD5,PARP-5a,PARP5A,PARPL,TIN1,TINF1,TNKS1,pART5,tankyrase,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Wnt/β-Catenin Signaling Pathway,TNKS
    分子量
    67kDa/142kDa
    基因ID
    8658
    UniProt
    O95271
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