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- 抗原 See all SUV39H2 抗体
- SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This SUV39H2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- KMT1B / SUV39H2 Rabbit mAb
- 交叉反应
- 人
- 产品特性
- Monoclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthesized peptide derived from human KMT1B / SUV39H2
- 亚型
- IgG
- Top Product
- Discover our top product SUV39H2 Primary Antibody
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anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) antibody
SUV39H2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 360-390) antibodySUV39H2 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 93-122) antibodySUV39H2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 201-410) antibodySUV39H2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 308-337) antibodySUV39H2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 93-122), (N-Term) antibodySUV39H2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB02737 unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (Internal Region) antibodySUV39H2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (Internal Region) antibodySUV39H2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 141-350) antibodySUV39H2 适用: 人 WB, ChIP, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 360-390), (C-Term) antibodySUV39H2 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB02739 unconjugated
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- 应用备注
- WB,1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
- 别名
- SUV39H2 (SUV39H2 产品)
- 别名
- KMT1B antibody, 4930507K23Rik antibody, AA536750 antibody, D030054H19Rik antibody, D2Ertd544e antibody, SUV39H2 antibody, kmt1b antibody, suppressor of variegation 3-9 homolog 2 antibody, suppressor of variegation 3-9 homolog 2 (Drosophila) antibody, suppressor of variegation 3-9 homolog 2 L homeolog antibody, SUV39H2 antibody, Suv39h2 antibody, suv39h2 antibody, suv39h2.L antibody
- 背景
- Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5 proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher-order chromatin organization during spermatogenesis. Recruited by the large PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1, contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation.,KMT1B,Apoptosis,Cell Biology & Developmental Biology,Chromatin Remodeling,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Methylation,Epigenetics & Nuclear Signaling,SUV39H2
- 分子量
- 47kDa
- 基因ID
- 79723
- UniProt
- Q9H5I1
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