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STIM1 抗体

STIM1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7270609
发货至: 中国
  • 抗原 See all STIM1 抗体
    STIM1 (Stromal Interaction Molecule 1 (STIM1))
    适用
    • 73
    • 56
    • 26
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 78
    • 8
    • 1
    • 1
    克隆类型
    • 72
    • 16
    单克隆
    标记
    • 40
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    • 3
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    • 2
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    • 2
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    • 1
    This STIM1 antibody is un-conjugated
    应用范围
    • 44
    • 31
    • 26
    • 26
    • 25
    • 19
    • 10
    • 10
    • 8
    • 6
    • 3
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    • 1
    Western Blotting (WB)
    原理
    STIM1 Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human STIM1
    亚型
    IgG
    Top Product
    Discover our top product STIM1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    STIM1 (Stromal Interaction Molecule 1 (STIM1))
    别名
    STIM1 (STIM1 产品)
    别名
    stim1 antibody, MGC76045 antibody, STIM1 antibody, si:dkey-24p1.5 antibody, MGC154748 antibody, si:ch211-112l17.2 antibody, Stim1 antibody, D11S4896E antibody, GOK antibody, TAM antibody, SIM antibody, stromal interaction molecule 1 antibody, stromal interaction molecule 1a antibody, stromal interaction molecule 1 L homeolog antibody, stromal interaction molecule 1b antibody, STIM1 antibody, stim1 antibody, stim1a antibody, stim1.L antibody, stim1b antibody, Stim1 antibody
    背景
    This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013],D11S4896E, GOK, IMD10, STRMK, TAM, TAM1,Apoptosis,B Cell Receptor Signaling Pathway,Calcium Signaling,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Immunology & Inflammation,Neuroscience,Signal Transduction,STIM1
    分子量
    77kDa
    基因ID
    6786
    UniProt
    Q13586
    途径
    TCR Signaling, BCR Signaling
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