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DCUN1D1 抗体 (AA 101-200)

DCUN1D1 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN717551
发货至: 中国
  • 抗原 See all DCUN1D1 抗体
    DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
    抗原表位
    • 14
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 101-200
    适用
    • 35
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    宿主
    • 29
    • 4
    • 2
    克隆类型
    • 32
    • 3
    多克隆
    标记
    • 16
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DCUN1D1 antibody is un-conjugated
    应用范围
    • 31
    • 14
    • 12
    • 12
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SCRO/DCUN1D1
    亚型
    IgG
    Top Product
    Discover our top product DCUN1D1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
    别名
    SCRO (DCUN1D1 产品)
    别名
    fd19a01 antibody, zgc:66414 antibody, wu:fd19a01 antibody, dcun1l1 antibody, rp42 antibody, sccro antibody, scro antibody, tes3 antibody, DCNL1 antibody, DCUN1L1 antibody, RP42 antibody, SCCRO antibody, SCRO antibody, Tes3 antibody, Rp42 antibody, pTes3 antibody, DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) antibody, DCN1-like protein 1 antibody, DCN1, defective in cullin neddylation 1, domain containing 1 L homeolog antibody, defective in cullin neddylation 1 domain containing 1 antibody, dcun1d1 antibody, dcnl1 antibody, dcun1d1.L antibody, DCUN1D1 antibody, Dcun1d1 antibody
    背景

    Synonyms: DCN1 defective in cullin neddylation 1 domain containing 1, DCN1 like protein 1, DCUN1 domain containing protein 1, DCUN1L1, Defective in cullin neddylation protein 1 like protein 1, RP 42, RP42, RP42 homolog, SCCRO, SCRO, Squamous cell carcinoma related oncogene, Tes 3, Tes3.

    Background: DCUN1D1 (DCUN1 domain-containing protein 1) contains a DUF298 domain and a UBA-like ubiquitin. Forms part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression. Defects in DCUN1D1 may be a cause of squamous cell carcinomas.Strongly overexpressed in thyroid tumors, bronchioloalveolar carcinomas, and malignant tissues of squamous cell carcinoma of the oral tongue. Not overexpressed in aggressive adrenocortical carcinomas.

    基因ID
    54165
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