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SPTA1 抗体

This anti-SPTA1 antibody is a 兔 单克隆 antibody detecting SPTA1 in WB. Suitable for 人.
产品编号 ABIN7270517
发货至: 中国

Quick Overview for SPTA1 抗体 (ABIN7270517)

抗原

See all SPTA1 抗体
SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

适用

  • 67
  • 13
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宿主

  • 39
  • 29

克隆类型

  • 54
  • 14
单克隆

标记

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  • 1
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This SPTA1 antibody is un-conjugated

应用范围

  • 51
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  • 40
  • 9
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Western Blotting (WB)
  • 原理

    alpha 1 Spectrin Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human alpha 1 Spectrin

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

    别名

    SPTA1

    背景

    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia. [provided by RefSeq, Jul 2008],EL2, HPP, HS3, SPH3, SPTA,Blood,Blood_Blood Cell Antigens,Cardiovascular,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Signal Transduction,SPTA1

    分子量

    280kDa

    基因ID

    6708

    UniProt

    P02549

    途径

    Regulation of Actin Filament Polymerization
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