RUNX2 抗体
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北京 101111
Quick Overview for RUNX2 抗体 (ABIN7270117)
抗原
See all RUNX2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RUNX2 Rabbit mAb
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交叉反应
- 人, 小鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human RUNX2
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IP,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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别名
- RUNX2
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背景
- This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016],AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Extracellular Matrix,Extracellular Matrix_Bone,Hippo Signaling Pathway,Mesenchymal Stem Cells,Stem Cells,TGF-b-Smad Signaling Pathway_Target gene,Transcription Factors,RUNX2
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分子量
- kDa
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基因ID
- 860
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UniProt
- Q13950
抗原
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