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RUNX2 抗体 (N-Term)

Cited in 2+ publications. The 兔多克隆 anti-RUNX2 antibody (ABIN2780588) specifically detects RUNX2 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 豚鼠, Cow, 马和斑马鱼 samples.

WB Suggested Anti-RUNX2 Antibody Titration: 0. (RUNX2 抗体 (N-Term))

Sample Type: Lane 1:241 µg mouse mesenchymal stem cell lysate Primary Antibody Dilution: 1:0000Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:00,000 Color/Signal Descriptions: RUNX2 Gene Name: Anonymous Submitted by: (RUNX2 抗体 (N-Term))

Host: Rabbit Target Name: RUNX2 Sample Type: Human Adult Placenta Antibody Dilution: 1. (RUNX2 抗体 (N-Term))

5 images

(2 references)

产品编号 ABIN2780588

发货至: 中国

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Quick Overview for RUNX2 抗体 (N-Term) (ABIN2780588)

抗原

See all RUNX2 抗体

RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

适用

人, 小鼠, 大鼠, 豚鼠, Cow, 马, 斑马鱼

宿主

兔

克隆类型

多克隆

标记

This RUNX2 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product RUNX2 Primary Antibody

抗原表位
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16

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2

2

2

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2

2

1

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1

1

1

1
N-Term

原理

RUNX2 Antibody - N-terminal region

序列

MRIPVDPSTS RRFSPPSSSL QPGKMSDVSP VVAAQQQQQQ QQQQQQQQQQ

预测反应

Cow: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

产品特性

This is a rabbit polyclonal antibody against RUNX2. It was validated on Western Blot.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human RUNX2
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 242-521) antibody
RUNX2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibody
RUNX2 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F5 unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibody
RUNX2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D8 unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 300-350) antibody
RUNX2 适用: 人, 小鼠 WB, IHC, ICC, IP 宿主: 兔 Monoclonal BLR360N unconjugated Recombinant Antibody

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 445-474) antibody
RUNX2 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibody
RUNX2 适用: 人, 大鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 3F5 unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 300-350) antibody
RUNX2 适用: 人, 小鼠 WB, IHC, ICC, IP 宿主: 兔 Monoclonal BLR360N unconjugated Recombinant Antibody

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibody
RUNX2 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D8 unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) antibody
RUNX2 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 445-474) antibody
RUNX2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB15321 unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38452-100UG

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

prevent freeze-thaw cycles

储存条件

4 °C,-20 °C

储存方法

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Li, Fan, Chen, Yang, Su, Bi: "Construction of adipose scaffold for bone repair with gene engineering bone cells." in: Experimental biology and medicine (Maywood, N.J.), Vol. 238, Issue 12, pp. 1350-4, (2013) (PubMed).

Lee, Lee, Ryoo, Park, Park, Bae, Cho, Park: "The odontogenic ameloblast-associated protein (ODAM) cooperates with RUNX2 and modulates enamel mineralization via regulation of MMP-20." in: Journal of cellular biochemistry, Vol. 111, Issue 3, pp. 755-67, (2010) (PubMed).
抗原

RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

别名

RUNX2

背景

Background Information: RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants, encoding different protein isoforms, result from alternate promoter use as well as alternate splicing.
Gene Name: Runt-related transcription factor 2
Alternative Symbols: CCD, AML3, CCD1, CLCD, OSF2, CBFA1, OSF-2, PEA2aA, PEBP2aA, CBF-alpha-1
Protein Name: Runt-related transcription factor 2

分子量

55kDa

基因ID

860

NCBI登录号

NP_004339

UniProt

Q13950