Raptor 抗体
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北京 101111
Quick Overview for Raptor 抗体 (ABIN7269900)
抗原
See all Raptor (RPTOR) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Raptor Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human Raptor
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Raptor (RPTOR) (Regulatory Associated Protein of mTOR, Complex 1 (RPTOR))
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别名
- RPTOR
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背景
- This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],KOG1, Mip1,AMPK Signaling Pathway,Autophagy,Autophagy_Regulator,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Insulin Receptor Signaling Pathway,mTOR Signaling Pathway,PI3K-Akt Signaling Pathway,Signal Transduction,T Cell Receptor Signaling Pathway,Translation Control,Translational Control_Regulation of eIF4 and p70 S6 Kinase,RPTOR
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分子量
- 149kDa
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基因ID
- 57521
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UniProt
- Q8N122
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途径
- PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Autophagy, BCR Signaling, Warburg Effect
抗原
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