Phospholipase C gamma 2 抗体
Quick Overview for Phospholipase C gamma 2 抗体 (ABIN7269342)
抗原
See all Phospholipase C gamma 2 (PLCG2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- PLC gamma 2 (PLCG2) Rabbit mAb
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Monoclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- A synthesized peptide derived from human PLC gamma 2 (PLC gamma 2 (PLCG2))
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Phospholipase C gamma 2 (PLCG2)
-
别名
- PLCG2
-
背景
- The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014],APLAID, FCAS3, PLC-IV, PLC-gamma-2,Angiogenesis,B Cell Receptor Signaling Pathway,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Actins,Endocrine & Metabolism,ErbB-HER Signaling Pathway,Immunology & Inflammation,Lipid Metabolism,Lipid Metabolism_Hydrolysis,Lipids,MAPK-Erk Signaling Pathway,Protein phosphorylation,Signal Transduction,PLCG2
-
分子量
- 148kDa
-
基因ID
- 5336
-
UniProt
- P16885
-
途径
- RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
抗原
-