PAK1 抗体
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北京 101111
Quick Overview for PAK1 抗体 (ABIN7269144)
抗原
See all PAK1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PAK1 Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human PAK1.
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PAK1 (P21-Activated Kinase 1 (PAK1))
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别名
- PAK1
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背景
- This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010],PAK1,PAKalpha,Apoptosis,Cancer,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Actins,Cytoskeleton_Microtubules,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,MAPK-Erk Signaling Pathway,Protein phosphorylation,Signal Transduction,TGF-b-Smad Signaling Pathway,PAK1
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分子量
- 66kDa
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基因ID
- 5058
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UniProt
- Q13153
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途径
- MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
抗原
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