MGMT 抗体
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北京 101111
Quick Overview for MGMT 抗体 (ABIN7269075)
抗原
See all MGMT 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MGMT Rabbit mAb
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交叉反应
- 人
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human MGMT
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
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别名
- MGMT
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背景
- Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015],MGMT, O-6-methylguanine-DNA methyltransferase,DNA Damage & Repair,Epigenetics & Nuclear Signaling,MGMT
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分子量
- 22kDa
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基因ID
- 4255
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UniProt
- P16455
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途径
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
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