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IGF1R 抗体 (pTyr1131, pTyr1146)

This anti-IGF1R antibody is a 兔 多克隆 antibody detecting IGF1R in WB. Suitable for 人.
产品编号 ABIN7267901
发货至: 中国

Quick Overview for IGF1R 抗体 (pTyr1131, pTyr1146) (ABIN7267901)

抗原

See all IGF1R 抗体
IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

适用

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宿主

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克隆类型

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多克隆

标记

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This IGF1R antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    pTyr1131, pTyr1146

    原理

    Phospho-INSR-Y1146/IGF1R-Y1131 Rabbit pAb

    交叉反应

    产品特性

    Phosphorylated Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic phosphorylated peptide around Y1146 of human INSR and Y1131 of human IGF1R.

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

    别名

    IGF1R/INSR

    背景

    This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],INSR/IGF1R,Protein phosphorylation,Protein phosphorylation,Protein phosphorylation,IGF1R/INSR

    分子量

    155kDa

    基因ID

    3643, 3480

    UniProt

    P06213, P08069

    途径

    RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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