GTPase NRas 抗体 (AA 1-189)
Quick Overview for GTPase NRas 抗体 (AA 1-189) (ABIN7267532)
抗原
See all GTPase NRas (NRAS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-189
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原理
- NRAS Rabbit pAb
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序列
- MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNSKSF ADINLYREQI KRVKDSDDVP MVLVGNKCDL PTRTVDTKQA HELAKSYGIP FIETSAKTRQ GVEDAFYTLV REIRQYRMKK LNSSDDGTQG CMGLPCVVM
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-189 of human NRAS (NP_002515.1).
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亚型
- IgG
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anti-GTPase NRas (NRAS) (Internal Region) antibody
Verified NRAS 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-GTPase NRas (NRAS) (AA 72-101) antibodyNRAS 适用: 人 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-GTPase NRas (NRAS) (AA 147-179) antibodyNRAS 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-GTPase NRas (NRAS) (AA 101-189) antibodyNRAS 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GTPase NRas (NRAS) (AA 91-140) antibodyNRAS 适用: 人, 大鼠, 小鼠, 兔, Cow, 豚鼠, 马, 斑马鱼, Bat, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GTPase NRas (NRAS) antibodyNRAS 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-GTPase NRas (NRAS) (AA 72-101), (N-Term) antibodyNRAS 适用: 人, 大鼠, 小鼠 WB, FACS, IF 宿主: 兔 Polyclonal RB14459 unconjugated
anti-GTPase NRas (NRAS) (AA 1-186) antibodyNRAS 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GTPase NRas (NRAS) antibodyNRAS 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB56819 unconjugated
anti-GTPase NRas (NRAS) (AA 90-189) antibodyNRAS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A3 unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GTPase NRas (NRAS)
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别名
- NRAS
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背景
- This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.,NRAS,ALPS4,CMNS,N-ras,NCMS,NRAS1,NS6,Cancer,Signal Transduction,G protein signaling,Signal Transduction,G2/M DNA Damage Checkpoint,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Warburg Effect,Immunology & Inflammation,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,NF-kB Signaling Pathway,NRAS
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分子量
- 21kDa
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基因ID
- 4893
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UniProt
- P01111
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途径
- p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
抗原
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