This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011],ALPS4, CMNS, N-ras, NCMS, NRAS1, NS6,Cancer,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Actins,Endocrine & Metabolism,ErbB-HER Signaling Pathway,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,G protein signaling_Small G proteins,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Insulin Receptor Signaling Pathway,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,NF-kB Signaling Pathway,Signal Transduction,T Cell Receptor Signaling Pathway,Warburg Effect,NRAS