Gelsolin 抗体 (AA 543-782)
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北京 101111
Quick Overview for Gelsolin 抗体 (AA 543-782) (ABIN7267365)
抗原
See all Gelsolin (GSN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 543-782
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原理
- Gelsolin Rabbit pAb
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序列
- PMIIYKGGTS REGGQTAPAS TRLFQVRANS AGATRAVEVL PKAGALNSND AFVLKTPSAA YLWVGTGASE AEKTGAQELL RVLRAQPVQV AEGSEPDGFW EALGGKAAYR TSPRLKDKKM DAHPPRLFAC SNKIGRFVIE EVPGELMQED LATDDVMLLD TWDQVFVWVG KDSQEEEKTE ALTSAKRYIE TDPANRDRRT PITVVKQGFE PPSFVGWFLG WDDDYWSVDP LDRAMAELAA
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 543-782 of human Gelsolin (NP_000168.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Gelsolin (GSN)
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别名
- GSN
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背景
- The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.,GSN;ADF;AGEL;gelsolin,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Microfilaments,Actins,GSN
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分子量
- 80kDa/81kDa/85kDa
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基因ID
- 2934
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UniProt
- P06396
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途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
抗原
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