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CTCF 抗体

This anti-CTCF antibody (ABIN7266164) is a Rabbit Monoclonal antibody detecting CTCF in WB, IF, IP, ChIP. Suitable for Human.
产品编号 ABIN7266164
发货至: 中国

Quick Overview for CTCF 抗体 (ABIN7266164)

抗原

See all CTCF 抗体
CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

适用

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宿主

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克隆类型

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单克隆

标记

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This CTCF antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)
  • 原理

    CTCF Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human CTCF.

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200,ChIP,1:20 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

    别名

    CTCF

    背景

    This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010],CTCF;MRD21;CTCF,Epigenetics & Nuclear Signaling,CTCF

    分子量

    140kDa

    基因ID

    10664

    UniProt

    P49711
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