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- 抗原 See all CIC 抗体
- CIC (Capicua Homolog (CIC))
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抗原表位
- AA 1379-1608
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CIC antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- CIC Rabbit pAb
- 序列
- LATSPRAILG SYRKKRKNST DLDSAPEDPT SPKRKMRRRS SCSSEPNTPK SAKCEGDIFT FDRTGTEAED VLGELEYDKV PYSSLRRTLD QRRALVMQLF QDHGFFPSAQ ATAAFQARYA DIFPSKVCLQ LKIREVRQKI MQAATPTEQP PGAEAPLPVP PPTGTAAAPA PTPSPAGGPD PTSPSSDSGT AQAAPPLPPP PESGPGQPGW EGAPQPSPPP PGPSTAATGR
- 交叉反应
- 人, 小鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1379-1608 of human CIC (NP_055940.3).
- 亚型
- IgG
- Top Product
- Discover our top product CIC Primary Antibody
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anti-Capicua Homolog (CIC) (N-Term) antibody
CIC 适用: 小鼠, 人, 大鼠, 兔, Cow, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Capicua Homolog (CIC) (AA 1475-1560) antibodyCIC 适用: 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Capicua Homolog (CIC) (N-Term) antibodyCIC 适用: 小鼠, 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Capicua Homolog (CIC) antibodyCIC WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Capicua Homolog (CIC) (AA 174-203), (N-Term) antibodyCIC 适用: 小鼠, 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24284 unconjugated
anti-Capicua Homolog (CIC) (AA 177-207), (N-Term) antibodyCIC 适用: 小鼠, 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:200 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CIC (Capicua Homolog (CIC))
- 别名
- CIC (CIC 产品)
- 别名
- wu:fb93c01 antibody, CIC antibody, 1200010B10Rik antibody, mKIAA0306 antibody, capicua transcriptional repressor b antibody, capicua transcriptional repressor antibody, cicb antibody, CIC antibody, Cic antibody
- 背景
- The protein encoded by this gene is an ortholog of the Drosophila melanogaster capicua gene, and is a member of the high mobility group (HMG)-box superfamily of transcriptional repressors. This protein contains a conserved HMG domain that is involved in DNA binding and nuclear localization, and a conserved C-terminus. Studies suggest that the N-terminal region of this protein interacts with Atxn1 (GeneID:6310), to form a transcription repressor complex, and in vitro studies suggest that polyglutamine-expansion of ATXN1 may alter the repressor activity of this complex. Mutations in this gene have been associated with olidogdendrogliomas (PMID:21817013). In addition, translocation events resulting in gene fusions of this gene with both DUX4 (GeneID:100288687) and FOXO4 (GeneID:4303) have been associated with round cell sarcomas. There are multiple pseudogenes of this gene found on chromosomes 1, 4, 6, 7, 16, 20, and the Y chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.,CIC,Epigenetics & Nuclear Signaling,Neuroscience,Neurodegenerative Diseases,CIC
- 分子量
- 163kDa
- 基因ID
- 23152
- UniProt
- Q96RK0
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