ADAM-TS7 antibody, ADAMTS7B antibody, ADAM-TS 7 antibody, ADAMTS-7 antibody, COMPase antibody, ADAM metallopeptidase with thrombospondin type 1 motif 7 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 7 antibody, ADAMTS7 antibody, Adamts7 antibody
背景
The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration. Mutations in this gene may be associated with susceptibility to coronary artery disease.,ADAMTS7,ADAM-TS 7,ADAM-TS7,ADAMTS-7,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,ADAM Protein Family,Ubiquitin,ADAMTS7