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SNCA 抗体 (AA 117-131)

SNCA 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7211663
发货至: 中国
  • 抗原 See all SNCA 抗体
    SNCA (Synuclein, alpha (SNCA))
    抗原表位
    • 73
    • 31
    • 28
    • 23
    • 16
    • 15
    • 12
    • 11
    • 11
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 117-131
    适用
    • 291
    • 199
    • 198
    • 14
    • 10
    • 10
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 237
    • 97
    • 4
    • 1
    • 1
    • 1
    克隆类型
    • 222
    • 120
    多克隆
    标记
    • 143
    • 25
    • 22
    • 17
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    This SNCA antibody is un-conjugated
    应用范围
    • 237
    • 165
    • 109
    • 80
    • 75
    • 68
    • 68
    • 52
    • 48
    • 44
    • 23
    • 21
    • 10
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    This antibody has been shown to react strongly with human brain-derived α-synuclein. The antibody also reacts with rat brain-derived α-synuclein but reactivity appears substantially less than with human.
    交叉反应 (详细)
    Does not cross-react with mouse α-synuclein.
    产品特性
    NACP| Non-A β component of senile plaques,alpha-Synuclein polyclonal antibody
    纯化方法
    Purified by caprylic acid and ammonium sulphate precipitation.,Purified from rabbit serum. Vial contains an immunoglobulin preparation, partially purified by chromatography from whole serum, suspended in phosphate-buffered saline (pH 7.4) containing 0.01M sodium azide.
    免疫原
    Synthetic peptide corresponding to [Cys] + aa 117-131 of human alpha-synuclein conjugated to KLH. The sequence is conserved in rat alpha-synuclein except for two substitutions, namely Asp121Ser and Asn122Ser.
    Top Product
    Discover our top product SNCA Primary Antibody
  • 应用备注
    Western blot (1:1,000-1:20,000)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.,Western blot: The antibody has been characterized by single dimension SDS-PAGE using recombinant α- and β-synucleins as well as rat, mouse and human brain lysates with and without peptide blockade. Studies with the recombinant proteins demonstrated the absolute specificity of the antibody for α-synuclein. The antibody gives a strong band at a relative molecular weight of approximately 15 kDa with human brain lysate which is wholly abolished by preincubation with the immunizing peptide (Prod. No. BML-SP9340).Immunohistochemistry: The antibody has been tested on de-waxed tissue sections of human brain fixed in neutral buffered formaldehyde. A standard protocol should be followed.
    说明

    For Blocking peptide see Prod. No. BML-SP9340.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. In PBS, pH 7.4, containing 10 mM sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20 °C.
    储存条件
    -20 °C
    储存方法
    Store unopened vial at -20°C until required for use. AVOID REPEATED FREEZE-THAW CYCLES. Aliquot undiluted antibody into smaller volumes (not less than 10μL) prior to freezing if appropriate. The use of high quality 'antiserum-grade' plastic or glass vials is recommended. Store diluted antibody at 2-4°C (do not freeze) and use within 1 month. Dilute to working strength with 50mM PBS (pH 7.4) containing 1.5% sodium chloride and 1% normal goat serum (if a goat anti-rabbit IgG linker antibody is to be used).
  • 抗原
    SNCA (Synuclein, alpha (SNCA))
    别名
    alpha-Synuclein (SNCA 产品)
    别名
    snca antibody, MGC64356 antibody, LOC619283 antibody, NACP antibody, alphaSYN antibody, PARK1 antibody, PARK4 antibody, PD1 antibody, synuclein alpha L homeolog antibody, alpha-synuclein antibody, synuclein alpha antibody, synuclein, alpha antibody, snca.L antibody, LOC619283 antibody, SNCA antibody, Snca antibody
    UniProt
    P37840
    途径
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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