RELB 抗体 (pSer552)
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北京 101111
Quick Overview for RELB 抗体 (pSer552) (ABIN7223982)
抗原
See all RELB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer552
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原理
- RelB (phospho Ser552) Polyclonal Antibody
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特异性
- Phospho-RelB (S552) Polyclonal Antibody detects endogenous levels of RelB protein only when phosphorylated at S552.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human RelB Phospho-Ser552
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亚型
- IgG
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anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (AA 1-579) antibody
RELB 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (AA 1-579) antibodyRELB 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) antibodyKD Validated RELB 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB925 unconjugated Recombinant Antibody
anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (C-Term) antibodyRELB 适用: 人, 小鼠 WB, IP, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated
anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (pSer573) antibodyRELB 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (AA 248-492) antibodyRELB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (AA 161-260) antibodyRELB 适用: 人, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) antibodyRELB 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 4C5 unconjugated
anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (AA 400-579) antibodyRELB 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) antibodyRELB 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB7180 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))
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别名
- RelB
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背景
- Rabbit Anti-RelB (phospho Ser552) Polyclonal Antibody,RELB, Transcription factor RelB, I-Rel,Transcription factors of the nuclear factor κB (NF-κB)/Rel family play a pivotal role in inflammatory and immune responses. There are five family members in mammals: relA, c-Rel, RelB, NF-κB1 (p105/p50), and NF-κB2 (p100/p52). Both p105 and p100 are proteolytically processed by the proteasome to produce p50 and p52, respectively. Rel proteins bind p50 and p52 to form dimeric complexes that bind DNA and regulate transcription. In unstimulated cells, NF-κB is sequestered in the cytoplasm by IκB inhibitory proteins. NF-κB-activating agents can induce the phosphorylation of IκB proteins, targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression. NIK and IKKα (IKK1) regulate the phosphorylation and processing of NF-κB2 (p100) to produce p52, which translocates to the nucleus.,Transcription factor RelB
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分子量
- observerd band 62kDa
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基因ID
- 5971
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UniProt
- Q01201
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途径
- NF-kappaB Signaling, RTK signaling
抗原
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