MYBL2 抗体 (pSer577)
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Quick Overview for MYBL2 抗体 (pSer577) (ABIN7222590)
抗原
See all MYBL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer577
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原理
- B-Myb (phospho Ser577) Polyclonal Antibody
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特异性
- Phospho-B-Myb (S577) Polyclonal Antibody detects endogenous levels of B-Myb protein only when phosphorylated at S577.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human B-Myb Phospho-Ser577
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))
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别名
- B-Myb
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背景
- Rabbit Anti-B-Myb (phospho Ser577) Polyclonal Antibody,MYBL2, BMYB, Myb-related protein B, B-Myb, Myb-like protein 2,The protein encoded by MYBL2, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene.,Myb-related protein B
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分子量
- observerd band 80kDa
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基因ID
- 4605
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UniProt
- P10244
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Chromatin Binding
抗原
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