Tuberin 抗体
Our Local Distributor
北京 101111
Quick Overview for Tuberin 抗体 (ABIN7224818)
抗原
See all Tuberin (TSC2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Tuberin Polyclonal Antibody
-
特异性
- Tuberin Polyclonal Antibody detects endogenous levels of Tuberin protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from human Tuberin around the non-phosphorylation site of S981
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
-
别名
- Tuberin
-
背景
- Rabbit Anti-Tuberin Polyclonal Antibody,TSC2, TSC4, Tuberin, Tuberous sclerosis 2 protein,Mutations in TSC2 (tuberous sclerosis 2) lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.,Tuberin
-
分子量
- observerd band 210kDa
-
基因ID
- 7249
-
UniProt
- P49815
-
途径
- RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
抗原
-