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Tuberin 抗体 (pThr1462)

This 兔 多克隆 anti-Tuberin antibody specifically detects Tuberin in ELISA, WB, IF 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7224812
发货至: 中国
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Quick Overview for Tuberin 抗体 (pThr1462) (ABIN7224812)

抗原

See all Tuberin (TSC2) 抗体
Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Tuberin antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pThr1462

    原理

    Tuberin (phospho Thr1462) Polyclonal Antibody

    特异性

    Phospho-Tuberin (T1462) Polyclonal Antibody detects endogenous levels of Tuberin protein only when phosphorylated at T1462.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Tuberin Phospho-Thr1462

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

    别名

    Tuberin

    背景

    Rabbit Anti-Tuberin (phospho Thr1462) Polyclonal Antibody,TSC2, TSC4, Tuberin, Tuberous sclerosis 2 protein,Mutations in TSC2 (tuberous sclerosis 2) lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.,Tuberin

    分子量

    observerd band 200kDa

    基因ID

    7249

    UniProt

    P49815

    途径

    RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
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