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TANK 抗体 (AA 140-220)

This 兔 多克隆 anti-TANK antibody specifically detects TANK in WB, ELISA, IF 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7218846
发货至: 中国
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Quick Overview for TANK 抗体 (AA 140-220) (ABIN7218846)

抗原

See all TANK 抗体
TANK (TRAF Family Member-Associated NFKB Activator (TANK))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This TANK antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 140-220

    原理

    TANK Polyclonal Antibody

    特异性

    TANK Polyclonal Antibody detects endogenous levels of TANK protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human TANK at AA range: 140-220

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    TANK (TRAF Family Member-Associated NFKB Activator (TANK))

    别名

    TANK

    背景

    Rabbit Anti-TANK Polyclonal Antibody,TANK, ITRAF, TRAF2, TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein, I-TRAF,The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The TRAF family member associated NFKB activator encoded by TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.,TRAF family member-associated NF-kappa-B activator

    分子量

    observerd band 48kDa

    基因ID

    10010

    UniProt

    Q92844

    途径

    p53 Pathway, TLR signaling, Activation of Innate immune Response
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