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RUNX2 抗体 (Internal Region)

This anti-RUNX2 antibody is a 兔 多克隆 antibody detecting RUNX2 in WB, ELISA 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7218244
发货至: 中国

Quick Overview for RUNX2 抗体 (Internal Region) (ABIN7218244)

抗原

See all RUNX2 抗体
RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

适用

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  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 128
  • 18

克隆类型

  • 108
  • 38
多克隆

标记

  • 67
  • 10
  • 7
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  • 1
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This RUNX2 antibody is un-conjugated

应用范围

  • 104
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  • 10
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  • 3
  • 1
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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 16
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    • 9
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    • 5
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    • 1
    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    Internal Region

    原理

    RUNX2 Polyclonal Antibody

    特异性

    RUNX2 Polyclonal Antibody detects endogenous levels of RUNX2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human RUNX2

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

    别名

    RUNX2

    背景

    Rabbit Anti-RUNX2 Polyclonal Antibody,RUNX2, AML3, CBFA1, OSF2, PEBP2A, Runt-related transcription factor 2, Acute myeloid leukemia 3 protein, Core-binding factor subunit alpha-1, CBF-alpha-1, Oncogene AML-3Osteoblast-specific transcription factor 2, OSF-2, Polyomavirus enhancer-binding protein 2 alpha A subunit, PEA2-alpha A, PEBP2-alpha A, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit,RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. Runt-related transcription factor 2 is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.,Runt-related transcription factor 2

    分子量

    observerd band 56kDa

    基因ID

    860

    UniProt

    Q13950
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