RHOA 抗体
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北京 101111
Quick Overview for RHOA 抗体 (ABIN7216826)
抗原
See all RHOA 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rho A Polyclonal Antibody
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特异性
- Rho A Polyclonal Antibody detects endogenous levels of Rho A protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Rho A around the non-phosphorylation site of S188
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RHOA (Ras Homolog Gene Family, Member A (RHOA))
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别名
- Rho A
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背景
- Rabbit Anti-Rho A Polyclonal Antibody,RHOA, ARH12, ARHA, RHO12, Transforming protein RhoA, Rho cDNA clone 12, h12,RHOA encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.,Transforming protein RhoA
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分子量
- observerd band 22kDa
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基因ID
- 387
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UniProt
- P61586
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途径
- Microtubule Dynamics, WNT signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interactome
抗原
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