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PPP1R13B 抗体 (AA 630-680)

This 兔 多克隆 anti-PPP1R13B antibody specifically detects PPP1R13B in ELISA 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7227388
发货至: 中国
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Quick Overview for PPP1R13B 抗体 (AA 630-680) (ABIN7227388)

抗原

See all PPP1R13B 抗体
PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

适用

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宿主

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克隆类型

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多克隆

标记

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This PPP1R13B antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 630-680

    原理

    ASPP1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of ASPP1

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human ASPP1 protein at AA range: 630-680

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

    别名

    ASPP1

    背景

    Rabbit Anti-ASPP1 Polyclonal Antibody,Apoptosis-stimulating of p53 protein 1, Protein phosphatase 1 regulatory subunit 13B,PPP1R13B encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. PPP1R13B (Protein Phosphatase 1 Regulatory Subunit 13B) is a Protein Coding gene. Among its related pathways are Activation of BH3-only proteins and TP53 Regulates Transcription of Cell Death Genes.,ASPP1

    基因ID

    23368

    UniProt

    Q96KQ4

    途径

    p53 Pathway
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