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PAK1 抗体 (pSer204)

This anti-PAK1 antibody is a 兔 多克隆 antibody detecting PAK1 in WB, ELISA 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7222894
发货至: 中国

Quick Overview for PAK1 抗体 (pSer204) (ABIN7222894)

抗原

See all PAK1 抗体
PAK1 (P21-Activated Kinase 1 (PAK1))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This PAK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    pSer204

    原理

    PAKα (phospho Ser204) Polyclonal Antibody

    特异性

    Phospho-PAKα (S204) Polyclonal Antibody detects endogenous levels of PAKα protein only when phosphorylated at S204.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human PAKalpha Phospho-Ser204

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PAK1 (P21-Activated Kinase 1 (PAK1))

    别名

    PAKalpha

    背景

    Rabbit Anti-PAKα (phospho Ser204) Polyclonal Antibody,PAK1, Serine/threonine-protein kinase PAK 1, Alpha-PAK, p21-activated kinase 1, PAK-1, p65-PAK,PAK1 encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,serine threonine-protein kinase PAK 1

    分子量

    observerd band 65kDa

    基因ID

    5058

    UniProt

    Q13153

    途径

    MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
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