NF-kB p65 抗体 (acLys314, acLys315)
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Quick Overview for NF-kB p65 抗体 (acLys314, acLys315) (ABIN7212366)
抗原
See all NF-kB p65 (NFkBP65) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- acLys314, acLys315
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原理
- Acetyl NF kB P65 (K314/K315) Mouse Monoclonal Antibody (2A11)
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特异性
- The antibody detects endogenous Acetyl NF kB P65 (K314/K315) protein.
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纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
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免疫原
- Synthetic Peptide of Acetyl NF kB P65 (K314/K315)
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亚型
- IgG1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
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别名
- NF kB P65
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背景
- Mouse Anti-Acetyl NF kB P65 (K314/K315) Mouse Monoclonal Antibody (2A11),Transcription factor p65, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3,NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA (RELA proto-oncogene, NF-kB subunit), or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of RELA, RELA. Four transcript variants encoding different isoforms have been found for RELA.,Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
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基因ID
- 5970
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UniProt
- Q04206
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途径
- NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins
抗原
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