NF-kB p65 抗体 (acLys314, Lys315)
Our Local Distributor
北京 101111
Quick Overview for NF-kB p65 抗体 (acLys314, Lys315) (ABIN7212366)
抗原
See all NF-kB p65 (NFkBP65) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- acLys314, Lys315
-
原理
- Mouse Anti-Acetyl NF kB P65 (K314/K315) Mouse Monoclonal Antibody (2A11)
-
特异性
- The antibody detects endogenous Acetyl NF kB P65 (K314/K315) protein.
-
纯化方法
- The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthetic Peptide of Acetyl NF kB P65 (K314/K315)
-
亚型
- IgG1
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300,IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
-
别名
- NF kB P65
-
背景
- Transcription factor p65, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA (RELA proto-oncogene, NF-kB subunit), or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of RELA, RELA. Four transcript variants encoding different isoforms have been found for RELA.
-
分子量
- 65kD
-
基因ID
- 5970
-
UniProt
- Q04206
-
途径
- NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins
抗原
-