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NFKBIB 抗体 (pSer23)

This 兔 多克隆 anti-NFKBIB antibody specifically detects NFKBIB in WB, ELISA, IHC (p) 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7213022
发货至: 中国
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Quick Overview for NFKBIB 抗体 (pSer23) (ABIN7213022)

抗原

See all NFKBIB 抗体
NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

适用

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人, 小鼠, 大鼠

宿主

  • 105
  • 10

克隆类型

  • 87
  • 28
多克隆

标记

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This NFKBIB antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

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    pSer23

    原理

    IκB-β (phospho Ser23) Polyclonal Antibody

    特异性

    Phospho-IκB-β (S23) Polyclonal Antibody detects endogenous levels of IκB-β protein only when phosphorylated at S23.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human IkappaB-beta Phospho-Ser23

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

    别名

    IkappaB-beta

    背景

    Rabbit Anti-IκB-β (phospho Ser23) Polyclonal Antibody,NFKBIB, IKBB, TRIP9, NF-kappa-B inhibitor beta, NF-kappa-BIB, I-kappa-B-beta, IkB-B, IkB-beta, IkappaBbeta, Thyroid receptor-interacting protein 9, TR-interacting protein 9, TRIP-9,NFKB inhibitor beta encoded by NFKBIB belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for NFKBIB.,NF-kappa-B inhibitor beta

    分子量

    observerd band 37kDa

    基因ID

    4793

    UniProt

    Q15653

    途径

    NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
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