MAP2K6 抗体 (pSer207)
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Quick Overview for MAP2K6 抗体 (pSer207) (ABIN7223624)
抗原
See all MAP2K6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer207
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原理
- MEK-6 (phospho Ser207) Polyclonal Antibody
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特异性
- Phospho-MEK-6 (S207) Polyclonal Antibody detects endogenous levels of MEK-6 protein only when phosphorylated at S207.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human MEK-6 Phospho-Ser207
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
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别名
- MEK-6
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背景
- Rabbit Anti-MEK-6 (phospho Ser207) Polyclonal Antibody,MAP2K6, MEK6, MKK6, PRKMK6, SKK3, Dual specificity mitogen-activated protein kinase kinase 6, MAP kinase kinase 6, MAPKK 6, MAPK/ERK kinase 6, MEK 6, Stress-activated protein kinase kinase 3, SAPK kinase 3, SAPKK-3, SAPKK3,MAP2K6 (mitogen-activated protein kinase kinase 6) encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, MAP2K6 is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.,Dual specificity mitogen-activated protein kinase kinase 6
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基因ID
- 5608
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UniProt
- P52564
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途径
- MAPK Pathway, TLR signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
抗原
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