FZD2 抗体 (AA 180-260)
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Quick Overview for FZD2 抗体 (AA 180-260) (ABIN7220862)
抗原
See all FZD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 180-260
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原理
- Frizzled-2 Polyclonal Antibody
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特异性
- Frizzled-2 Polyclonal Antibody detects endogenous levels of Frizzled-2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Frizzled-2 at AA range: 180-260
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- FZD2 (Frizzled Family Receptor 2 (FZD2))
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别名
- Frizzled-2
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背景
- Rabbit Anti-Frizzled-2 Polyclonal Antibody,FZD2, Frizzled-2, Fz-2, hFz2, FzE2,FZD2 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. FZD2 encodes frizzled class receptor 2 that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways. is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.,Frizzled-2
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分子量
- observerd band 55kDa
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基因ID
- 2535
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UniProt
- Q14332
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途径
- WNT signaling
抗原
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