FMO3 抗体 (Internal Region)
Quick Overview for FMO3 抗体 (Internal Region) (ABIN7218426)
抗原
See all FMO3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- FMO3 Polyclonal Antibody
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特异性
- FMO3 Polyclonal Antibody detects endogenous levels of FMO3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human FMO3
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亚型
- IgG
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anti-Flavin Containing Monooxygenase 3 (FMO3) antibody
FMO3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) (AA 1-532) antibodyFMO3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) antibodyFMO3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) (N-Term) antibodyFMO3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) (AA 81-130) antibodyFMO3 适用: 人, 大鼠, Cow, 犬, 马, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) (AA 1-532) antibodyFMO3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) (AA 30-56), (N-Term) antibodyFMO3 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21188 unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) (N-Term) antibodyFMO3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) antibodyFMO3 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) (AA 111-219) antibodyFMO3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- FMO3 (Flavin Containing Monooxygenase 3 (FMO3))
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别名
- FMO3
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背景
- Rabbit Anti-FMO3 Polyclonal Antibody,FMO3, Dimethylaniline monooxygenase [N-oxide-forming] 3, Dimethylaniline oxidase 3, FMO II, FMO form 2, Hepatic flavin-containing monooxygenase 3, FMO 3, Trimethylamine monooxygenase,Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor. In healthy individuals, trimethylamine is primarily converted to the non odorous trimethylamine N-oxide.,Dimethylaniline monooxygenase [N-oxide-forming] 3
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分子量
- observerd band 58kDa
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基因ID
- 2328
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UniProt
- P31513
抗原
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