XPO1 抗体 (acLys568)
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北京 101111
Quick Overview for XPO1 抗体 (acLys568) (ABIN7212648)
抗原
See all XPO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- acLys568
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原理
- CRM1 (Acetyl Lys568) Polyclonal Antibody
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特异性
- Acetyl-CRM1 (K568) Polyclonal Antibody detects endogenous levels of CRM1 protein only when non-acetylation at K568.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human CRM1 around the acetylation site of K568
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- XPO1 (Exportin 1 (XPO1))
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别名
- CRM1
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背景
- Rabbit Anti-CRM1 (Acetyl Lys568) Polyclonal Antibody,XPO1, CRM1, Exportin-1, Exp1, Chromosome region maintenance 1 protein homolog,This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. Exportin 1 also regulates NFAT and AP-1.,Exportin-1
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分子量
- observerd band 125kDa
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基因ID
- 7514
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UniProt
- O14980
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途径
- M Phase
抗原
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