XPO1 抗体 (C-Term)
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北京 101111
Quick Overview for XPO1 抗体 (C-Term) (ABIN2778849)
抗原
See all XPO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- XPO1 Antibody - C-terminal region
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序列
- NKLGGHITAE IPQIFDAVFE CTLNMINKDF EEYPEHRTNF FLLLQAVNSH
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against XPO1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human XPO1
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anti-Exportin 1 (XPO1) antibody
XPO1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Exportin 1 (XPO1) (AA 966-1071) antibodyXPO1 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF, ICC, IP, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 625-845) antibodyXPO1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) antibodyXPO1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 817-846), (C-Term) antibodyXPO1 适用: 人 FACS, IHC (p) 宿主: 兔 Polyclonal RB19972 unconjugated
anti-Exportin 1 (XPO1) (AA 917-1071) antibodyXPO1 适用: 人 WB, IHC, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 701-800) antibodyXPO1 适用: 人 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (C-Term) antibodyXPO1 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (Internal Region) antibodyXPO1 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) antibodyXPO1 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 9F2 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100094
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage." in: The Journal of cell biology, Vol. 221, Issue 3, (2022) (PubMed).
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- XPO1 (Exportin 1 (XPO1))
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别名
- XPO1
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背景
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Background Information: XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. XPO1 also regulates NFAT and AP-1.The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: Exportin 1 (CRM1 homolog, yeast)
Alternative Symbols: emb, CRM1, exp1, CRM-1
Protein Name: Exportin-1
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分子量
- 123 kDa
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基因ID
- 7514
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NCBI登录号
- NP_003391
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UniProt
- O14980
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途径
- M Phase
抗原
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