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Recombinant XPO1 抗体

XPO1 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 9F2 unconjugated Recombinant Antibody
产品编号 ABIN7127436
发货至: 中国
  • 抗原 See all XPO1 抗体
    XPO1 (Exportin 1 (XPO1))
    抗体类型
    Recombinant Antibody
    适用
    • 73
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    • 8
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    • 5
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    • 4
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    • 1
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    宿主
    • 68
    • 5
    克隆类型
    • 58
    • 15
    单克隆
    标记
    • 40
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    This XPO1 antibody is un-conjugated
    应用范围
    • 47
    • 16
    • 15
    • 14
    • 14
    • 14
    • 9
    • 7
    • 6
    • 6
    • 4
    • 2
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    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human CRM1
    克隆位点
    9F2
    亚型
    IgG
    Top Product
    Discover our top product XPO1 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    XPO1 (Exportin 1 (XPO1))
    别名
    XPO1 (XPO1 产品)
    别名
    CG13387 antibody, CRM1 antibody, Crm1 antibody, DCRM1 antibody, Dmel\\CG13387 antibody, Emb antibody, XPO-1 antibody, XPO1 antibody, Xpo1 antibody, crm1 antibody, dCRM1 antibody, l(2)k16715 antibody, 18.m06600 antibody, DDBDRAFT_0183812 antibody, DDBDRAFT_0234066 antibody, DDB_0183812 antibody, DDB_0234066 antibody, exportin-1 antibody, LOC100220104 antibody, emb antibody, exp1 antibody, Xpo antibody, AA420417 antibody, Exp1 antibody, embargoed antibody, exportin 1 antibody, putative exportin 1 antibody, chromosome region maintenance protein 1 antibody, exportin-1 antibody, exportin 1 (CRM1 homolog, yeast) antibody, exportin 1 S homeolog antibody, emb antibody, cgd3_3060 antibody, Tc00.1047053511725.150 antibody, Tb11.01.5940 antibody, BBOV_II007220 antibody, LMJF_32_1100 antibody, xpo1 antibody, Xpo1 antibody, XPO1 antibody, LOC100165622 antibody, LOC100633509 antibody, xpo1.S antibody
    背景

    Background: Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Involved in U3 snoRNA transport from Cajal bodies to nucleoli. Binds to late precursor U3 snoRNA bearing a TMG cap. Several viruses, among them HIV-1, HTLV-1 and influenza A use it to export their unspliced or incompletely spliced RNAs out of the nucleus. Interacts with, and mediates the nuclear export of HIV-1 Rev and HTLV-1 Rex proteins. Involved in HTLV-1 Rex multimerization.

    Aliases: Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog), XPO1, CRM1

    UniProt
    O14980
    途径
    M Phase
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