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DCLRE1C 抗体 (pSer516)

This anti-DCLRE1C antibody is a 兔 多克隆 antibody detecting DCLRE1C in WB, ELISA 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN7224264
发货至: 中国
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Quick Overview for DCLRE1C 抗体 (pSer516) (ABIN7224264)

抗原

See all DCLRE1C 抗体
DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

适用

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人, 小鼠

宿主

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克隆类型

  • 58
多克隆

标记

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This DCLRE1C antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pSer516

    原理

    Artemis (phospho Ser516) Polyclonal Antibody

    特异性

    Phospho-Artemis (S516) Polyclonal Antibody detects endogenous levels of Artemis protein only when phosphorylated at S516.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Artemis Phospho-Ser516

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

    别名

    Artemis

    背景

    Rabbit Anti-Artemis (phospho Ser516) Polyclonal Antibody,DCLRE1C, ARTEMIS, ASCID, SCIDA, SNM1C, Protein artemis, DNA cross-link repair 1C protein, Protein A-SCID, SNM1 homolog C, hSNM1C, SNM1-like protein,DCLRE1C encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in DCLRE1C can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants.,Protein artemis

    基因ID

    64421

    UniProt

    Q96SD1

    途径

    DNA Damage Repair
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