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DCLRE1C 抗体 (AA 482-531)

This 兔 多克隆 antibody specifically detects DCLRE1C in ELISA, IHC 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1532318
发货至: 中国
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Quick Overview for DCLRE1C 抗体 (AA 482-531) (ABIN1532318)

抗原

See all DCLRE1C 抗体
DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

适用

  • 70
  • 39
  • 26
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 68
  • 3
兔

克隆类型

  • 71
多克隆

标记

  • 35
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DCLRE1C antibody is un-conjugated

应用范围

  • 50
  • 24
  • 23
  • 13
  • 13
  • 8
  • 7
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 12
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 482-531

    原理

    Artemis Antibody

    特异性

    Artemis Polyclonal Antibody detects endogenous levels of Artemis protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Artemis. AA range:482-531

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

    别名

    Artemis

    背景

    Synonyms: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C; Protein artemis; DNA cross-link repair 1C protein; Protein A-SCID; SNM1 homolog C; hSNM1C; SNM1-like protein

    Background: This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],

    Gene Name: DCLRE1C

    Protein Name: Protein artemis

    分子量

    78 kDa

    基因ID

    64421

    OMIM

    602450

    UniProt

    Q96SD1

    途径

    DNA Damage Repair
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