DCLRE1C 抗体 (pSer516)
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Quick Overview for DCLRE1C 抗体 (pSer516) (ABIN1531298)
抗原
See all DCLRE1C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 482-531, pSer516
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原理
- Artemis (phospho Ser516) Antibody
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特异性
- Phospho-Artemis (S516) Polyclonal Antibody detects endogenous levels of Artemis protein only when phosphorylated at S516.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Artemis around the phosphorylation site of Ser516. AA range:482-531
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亚型
- IgG
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anti-DNA Cross-Link Repair 1C (DCLRE1C) (AA 21-50), (N-Term) antibody
DCLRE1C 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB24410 unconjugated
anti-DNA Cross-Link Repair 1C (DCLRE1C) (C-Term) antibodyDCLRE1C 适用: 人 WB, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-DNA Cross-Link Repair 1C (DCLRE1C) (AA 21-50) antibodyDCLRE1C 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DNA Cross-Link Repair 1C (DCLRE1C) (AA 301-400) antibodyDCLRE1C 适用: 人 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-DNA Cross-Link Repair 1C (DCLRE1C) (C-Term) antibodyDCLRE1C 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-DNA Cross-Link Repair 1C (DCLRE1C) (AA 396-445) antibodyDCLRE1C 适用: 人, 大鼠, 豚鼠, 马, 犬, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-DNA Cross-Link Repair 1C (DCLRE1C) (N-Term) antibodyDCLRE1C 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 兔, 斑马鱼, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-DNA Cross-Link Repair 1C (DCLRE1C) (C-Term) antibodyDCLRE1C 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA Cross-Link Repair 1C (DCLRE1C) (AA 1-434) antibodyDCLRE1C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
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别名
- Artemis
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背景
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Synonyms: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C; Protein artemis; DNA cross-link repair 1C protein; Protein A-SCID; SNM1 homolog C; hSNM1C; SNM1-like protein
Background: This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
Gene Name: DCLRE1C
Protein Name: Protein artemis
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分子量
- 78 kDa
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基因ID
- 64421
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OMIM
- 602450
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UniProt
- Q96SD1
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途径
- DNA Damage Repair
抗原
-
