DDR1 抗体 (pTyr513)
Quick Overview for DDR1 抗体 (pTyr513) (ABIN7228160)
抗原
See all DDR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr513
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原理
- DDR1 (Phospho-Tyr513) Polyclonal Antibody
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特异性
- This antibody detects endogenous levels of DDR1 when Phospho occurs at Tyr513
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human DDR1 (Phospho-Tyr513) Antibody protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
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别名
- DDR1
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背景
- Rabbit Anti-DDR1 (Phospho-Tyr513) Polyclonal Antibody,Epithelial discoidin domain-containing receptor 1, Epithelial discoidin domain receptor 1, CD167 antigen-like family member A, Cell adhesion kinase, Discoidin receptor tyrosine kinase, HGK2, Mammary carcinoma kinase 10, MCK-10, Protein-tyrosine kinase 3A, Protein-tyrosine kinase RTK-6, TRK E, Tyrosine kinase DDR, Tyrosine-protein kinase CAK, CD antigen CD167a,DDR1 (Discoidin Domain Receptor Tyrosine Kinase 1) is a Protein Coding gene. The protein encoded by DDR1 belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for DDR1.,DDR1
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分子量
- observerd band 130kDa
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基因ID
- 780
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UniProt
- Q08345
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途径
- RTK signaling, Smooth Muscle Cell Migration
抗原
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