DDR1 抗体
Quick Overview for DDR1 抗体 (ABIN7225020)
抗原
See all DDR1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DDR1 Polyclonal Antibody
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特异性
- DDR1 Polyclonal Antibody detects endogenous levels of DDR1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human CD167a around the non-phosphorylation site of Y792
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
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别名
- DDR1
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背景
- Rabbit Anti-DDR1 Polyclonal Antibody,DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE, Epithelial discoidin domain-containing receptor 1, Epithelial discoidin domain receptor 1, CD167 antigen-like family member A, Cell adhesion kinase, Discoidin receptor tyrosine kinase, HGK2,Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by DDR1 (discoidin domain receptor tyrosine kinase 1) belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for DDR1.,Epithelial discoidin domain-containing receptor 1
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分子量
- observerd band 100kDa
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基因ID
- 780
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UniProt
- Q08345
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途径
- RTK signaling, Smooth Muscle Cell Migration
抗原
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